Tatum Brown added 12 points Friday night and Monika Crank had 11 for the Wildcats. Arizona played without its top player, Angela Lackey, who was suspended for breaking a a team rule.
Arizona, which led 33-30 at the half, opened the second half with a 27-11 run, with Pickney scoring 10 points and Brown 7. Over the final 20 minutes, the Wildcats made 14-of-26 shots.
Pickney also had nine rebounds.
Stacey Dales led Oklahoma with 19 points, and Phylesha Whaley had 17.